Haneen A Al-Mazroua Selected Research

Autistic Disorder (Autism)

1/2022	Methylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism.
1/2022	CXCR2 antagonist SB332235 mitigates deficits in social behavior and dysregulation of Th1/Th22 and T regulatory cell-related transcription factor signaling in male BTBR T+ Itpr3tf/J mouse model of autism.
2/2021	5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism.
12/2020	3-Aminobenzamide alleviates elevated DNA damage and DNA methylation in a BTBR T+Itpr3tf/J mouse model of autism by enhancing repair gene expression.
10/2019	The histamine-4 receptor antagonist JNJ7777120 prevents immune abnormalities by inhibiting RORγt/T-bet transcription factor signaling pathways in BTBR T+ Itpr3tf/J mice exposed to gamma rays.

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Haneen A Al-Mazroua Research Topics

Disease

6	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 11/2023 - 01/2022
5	Autistic Disorder (Autism) 01/2022 - 10/2019
4	Inflammation (Inflammations) 10/2023 - 01/2022
3	Experimental Arthritis 06/2023 - 01/2020
2	Autism Spectrum Disorder 12/2020 - 06/2020
1	Tremor (Tremors) 12/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2023
1	Cognitive Dysfunction 12/2023
1	Multiple Sclerosis 11/2023
1	Neurodevelopmental Disorders 03/2023
1	Nervous System Diseases (Neurological Disorders) 01/2023
1	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 03/2022
1	Demyelinating Diseases (Demyelinating Disease) 01/2022
1	Encephalomyelitis (Myeloencephalitis) 01/2022
1	Memory Disorders (Memory Loss) 01/2022
1	Autoimmune Diseases (Autoimmune Disease) 01/2020
1	Rheumatoid Arthritis 01/2020
1	Hypertrophy 04/2013
1	Cardiomegaly (Heart Hypertrophy) 04/2013
1	Body Weight (Weight, Body) 04/2013
1	Cardiotoxicity 04/2013

Drug/Important Bio-Agent (IBA)

5	Transcription Factors (Transcription Factor)IBA 01/2022 - 10/2019
4	CytokinesIBA 01/2022 - 10/2019
3	Chemokine ReceptorsIBA 01/2023 - 01/2020
2	2- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA 11/2023 - 01/2023
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 06/2023 - 06/2020
1	Cadmium Chloride (Cadmium Dichloride)IBA 12/2023
1	Phosphotransferases (Kinase)IBA 11/2023
1	Histamine H4 ReceptorsIBA 10/2023
1	JNJ 10191584IBA 10/2023
1	Rituximab (Mabthera)FDA Link 06/2023
1	NSC 74859IBA 05/2023
1	NBI-74330IBA 05/2023
1	Heavy MetalsIBA 03/2023
1	Mitogen-Activated Protein KinasesIBA 01/2023
1	NF-kappa B (NF-kB)IBA 01/2023
1	Neuroprotective AgentsIBA 03/2022
1	purmorphamineIBA 03/2022
1	8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)IBA 03/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 03/2022
1	UCB 35625IBA 01/2022
1	SB-332235IBA 01/2022
1	methylmercuric chlorideIBA 01/2022
1	N- (3- propylcarbamoyloxirane- 2- carbonyl)- isoleucyl- prolineIBA 01/2022
1	D-Ala-peptide T-amideIBA 01/2022
1	Cathepsin BIBA 01/2022
1	CCR5 Receptors (CCR5 Receptor)IBA 01/2022
1	5-aminoisoquinolinoneIBA 02/2021
1	Interleukin-9 (Interleukin 9)IBA 02/2021
1	Interleukin-10 (Interleukin 10)IBA 02/2021
1	Therapeutic UsesIBA 02/2021
1	Interleukin-17 (Interleukin 17)IBA 02/2021
1	InterleukinsIBA 12/2020
1	3-aminobenzamideIBA 12/2020
1	DNA (Deoxyribonucleic Acid)IBA 12/2020
1	N- (1- (3- (4- ethoxyphenyl)- 4- oxo- 3,4- dihydropyrido(2,3- d)pyrimidin- 2- yl)ethyl)- N- pyridin- 3- ylmethyl- 2- (4- trifluoromethoxyphenyl)acetamideIBA 01/2020
1	CXCR3 ReceptorsIBA 01/2020
1	Messenger RNA (mRNA)IBA 04/2013
1	Atrial Natriuretic Factor (ANF)IBA 04/2013
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 04/2013
1	Creatine Kinase (Creatine Phosphokinase)IBA 04/2013
1	Proteins (Proteins, Gene)FDA Link 04/2013

Therapy/Procedure

3	Therapeutics 01/2022 - 12/2020